Approaches to the Potential Therapy of COVID-19: A General Overview from the Medicinal Chemistry PerspectiveCOVID-19의 잠재적 치료에 대한 접근: 의약 화학 관점의 일반 개요Review Published on 2022-01-202022-09-10 Journal: Molecules [Category] SARS, 변종, 치료제, [키워드] 3CLpro inhibitors active against affected Anti-inflammatory antibody Antiviral arising Cell characteristic charge Chemistry corticoids Corticosteroids COVID-19 pandemic cytokine Cytokine storm drug drugs targeting elongation factor Genome host cell host protein host proteins hyperinflammatory phase IL6 antibodies Inflammatory interleukin interleukin 6 involved Jak JAK-STAT inhibitors kinases less Mutation pharmacological treatment pharmacological treatments polyprotein Potential protease Protein RdRp inhibitors S antibodies SARS-CoV-2 SARS-CoV2 serine protease inhibitors sphingosine SphK2 inhibitors stages target the cell the disease therapeutic intervention triggered vaccination variants Viral viral entry viral genome viral infection Viral proteins virus [DOI] 10.3390/molecules27030658 PMC 바로가기 [Article Type] Review
Drug exposure may have a substantial influence on COVID-19 prognosis among residents of long-term care facilities: an exploratory analysis약물 노출은 장기 치료 시설 거주자들 사이에서 Covid-19 예후에 상당한 영향을 미칠 수 있습니다 : 탐색 적 분석Article Published on 2021-08-012022-08-31 Journal: International Journal of Infectious Diseases [Category] MERS, SARS, 치료제, [키워드] ACE2 ACE2 inhibitors age association blockers Care carried Case fatality rate Comorbidities Comorbidity corticoid corticoids COVID-19 COVID-19 disease COVID-19 prognosis cross-sectional cross-sectional study death Diagnosis disease drug drug exposure Exploratory analysis Fatality rate females individual Inhaled inhaled corticoids inhibitor inhibitors intake Long-term care long-term care facilities LTC moment Platelet Prevalence prevalent Prognosis prognostic Propensity score protective factor risk factor SARS-CoV-2 SARS-COV-2 infection socio-demographic statins statins. Vitamin Vitamin D [DOI] 10.1016/j.ijid.2021.07.007 PMC 바로가기 [Article Type] Article
First and second waves of coronavirus disease-19: A comparative study in hospitalized patients in Reus, Spain코로나바이러스 질병-19의 1차 및 2차 유행: 스페인 레우스의 입원 환자를 대상으로 한 비교 연구Research Article Published on 2021-03-312022-08-13 Journal: PLoS ONE [Category] Biology and Life Sciences, COVID-19, MERS, [키워드] age Anticoagulants cardiovascular diseases Case fatality rate Characteristics children Comorbidity coronavirus coronavirus disease Coronavirus disease-19 corticoids cough country diabetes Diabetes Mellitus difference duration of hospitalization Dyspnea Effect Europe Fatality rate Fever First wave followed by gastrointestinal symptoms help Hospitalized hospitalized patient Invasive mechanical ventilation less mechanical ventilation mortality risk factor mortality risk factors Neurological diseases Non-invasive non-invasive mechanical ventilation oxygen Oxygen therapy pandemic Patient Pneumonia pregnant renal reported SARS-CoV-2 second wave severity Signs and symptoms Spain spring Symptom the disease treated type 2 diabete Type 2 diabetes mellitus virus women [DOI] 10.1371/journal.pone.0248029 PMC 바로가기 [Article Type] Research Article
Comparison between first and second wave among critically ill COVID-19 patients admitted to a French ICU: no prognostic improvement during the second wave?Article Published on 2021-01-042023-06-14 Journal: Critical Care [Category] MERS, [키워드] ARDS corticoids COVID-19 France ICU Mortality SARS-CoV-2 [DOI] 10.1186/s13054-020-03449-6 PMC 바로가기
SARS-CoV-2 Treatment Approaches: Numerous Options, No Certainty for a Versatile VirusPharmacology Published on 2020-08-262022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] ACE2 receptor acting administration angiotensin-converting enzyme 2 receptors Antibiotics Antimalarial drugs Antiretrovirals antiviral activity approach certainty Clinical features convalescent plasma coronavirus coronavirus disease corticoids COVID-19 current therapy drug effective Endocytic pathway endocytosis Epitopes host-virus interaction Hydroxychloroquine identify immune immune response immune system disorders immunosuppressive drug Inflammatory cytokines initial interferons kinase inhibitors Mesenchymal stem cells monoclonal antibodies monoclonal antibody neutralization nucleotide analogue Numerous pandemic pathogenic mechanism pathogenic mechanisms promote Remdesivir RNA-dependent RNA polymerase Safe SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike protein SARS-CoV-2 vaccine Side effect similarity Spread stem cells Still therapeutic option therapeutic targets therapy Treatment Trial triggered Vaccine virus [DOI] 10.3389/fphar.2020.01224 PMC 바로가기 [Article Type] Pharmacology